Forskolin is a compound found in Coleus forskohlii, a tropical plant in the mint family. The plant is native to India, and grows wild in lots of countries in Southeast Asia. It’s been used since ancient times to deal with asthma, bronchitis, constipation, heart issues as well as other conditions. However, it became a lot more well known in 2014 after Dr. Oz praised it as a “miracle” weight-loss pill.
Forskolin is sold as an over the counter supplement usually containing 10-20% forskolin extract (known as pure forskolin). Manufacturers claim that it suppresses appetite so it helps with weight-loss. Summary: Forskolin is actually a compound based in the tropical plant Coleus forskohlii, part of the mint family. It’s been used since the past to treat various ailments, and is now marketed and sold as a weight loss pill.
How Is Forskolin Meant to Work? Forskolin has been studied being a potential weight-loss supplement because of the way it affects fat cells. In laboratory studies, forskolin causes fat cells to produce more cAMP (cyclic Adenosine Monophosphate), a chemical messenger that leads to the breakdown of fat tissue. Since forskolin causes the breakdown of fat cells in a lab, it’s thought to do the same in humans. That still remains unproven, however. Summary: Lab studies show that forskolin causes breakdown of fat tissue. It’s still unknown whether or not this has the same effect in your body.
Does Forskolin Cause Weight Loss? Does Forskolin Cause Weight-loss?Even when forskolin does cause fat tissue to breakdown, that doesn’t necessarily indicate it will lead to weight reduction. Only two small reports have looked at whether forskolin causes weight-loss in humans. In a clinical trial of 15 obese men, one group was given 500 mg of 10% forskolin extract on a daily basis. After 12 weeks, the body fat percentages in the men taking forskolin decreased significantly – from around 35% to 31% – in comparison to those given a placebo. Concurrently, lean body mass in men taking forskolin increased by about 5%. However, while fat mass declined and lean body mass increased, total bodyweight failed to change.
Interestingly, the audience taking forskolin also saw their testosterone levels increase, which may cause decreases in unwanted fat. Researchers have not examined how or if forskolin could cause testosterone levels to increase though. The other study found no influence on weight or excess fat in 19 overweight women using the same dosage of forskolin.
Summary: Very little studies have been done on forskolin and weight reduction. One small study thought it was decreased excess fat and increased lean body mass in males, however with no overall weight change. Another study on women found no influence on weight or body composition.
Does Forskolin Prevent Putting On Weight? Does Forskolin Prevent Putting On Weight?Although forskolin fails to appear to cause weight reduction, it may prevent putting on weight. Within the second study cited above, overweight women that took forskolin gained less weight over the course of 12 weeks compared to those given a placebo. However, the differences were small. The typical weight of ladies taking forskolin stayed approximately the same, as the average weight of the control group increased slightly (1.3 kg). The women failed to report any change in appetite. A study in rats also suggested that forskolin may prevent weight gain.
Researchers purposefully overfed rats so they would put on weight. The rats were separated into two groups – one received forskolin extract during the overfeeding period, one other failed to. The ones that received forskolin gained significantly less weight compared to other group – about 75% less. In addition, they ate less food and their levels of cholesterol improved significantly. While those two research has shown promising results, far more research is needed to see whether forskolin extract can prevent putting on weight in humans. Summary: Two small reports have learned that forskolin might help prevent weight gain. A lot more research is required to confirm this influence on humans.
Both studies of forskolin and weight in humans did not find any negative health consequences. Cholesterol, insulin and blood pressure levels levels were not affected, without any significant side effects were reported. In those studies, 100-250 ml of any 10% forskolin extract was used two times a day for 12 weeks. The consequences of using a greater dosage or utilizing it for an extended time are unknown.
One half of the nearly 1,300 reviews are 5 stars. Some people claimed to possess achieved significant weight-loss, even within the first to 2 weeks of taking. Other positive effects reported include: normalized bowel motions, decreased msvkiq and increased energy. Many reported weight-loss alongside diet and exercise (not simply through the pill itself).
Some individuals saw no improvement in weight or overall health. Others experienced side effects like diarrhea, bloating, gas, and constipation. A couple of noted its contraindication with their blood pressure medication.